doi: 10.1093/labmed/23.10.641pmid: N/A
Article PDF first page preview Close This content is only available as a PDF. © American Society of Clinical Pathologists
doi: 10.1093/labmed/23.10.645pmid: N/A
This content is only available as a PDF. © American Society of Clinical Pathologists
doi: 10.1093/labmed/23.10.648pmid: N/A
Abstract Cytodiagnosis involves a tiered system of screening, interpretation, and diagnosis. Cytotechnologists and cytopatbologists should be aware of the medical and legal consequences of their actions when performing their duties in the laboratory. This article describes actions for which cytopathology laboratory personnel may be held legally liable in a court of law. In addition, practical approaches to reducing the risk of liability are offered. This content is only available as a PDF. © American Society of Clinical Pathologists
Buchwald,, Henry;Rohde, Thomas, D.;Kryjeski, Sheila, R.
doi: 10.1093/labmed/23.10.652pmid: N/A
Abstract Portable insulin pumps have been used for the treatment of diabetes mellitus since the mid 1970s and are available from two manufacturers. Both are programmable syringe pumps and sell for about $3,600. Portable pumps can be a powerful tool for achieving and maintaining precise control of glycemia, but are most likely to improve quality of life in settings where paitents collaborate closely with medical professionals in the management of their disease. Implantable insulin delivery pumps are not yet FDA approved but are available in clinical trial. Decisions regarding which type I diabetic patients are suitable candidates for treatment by implantable pump cannot be meaningfully addressed at this time. Implantable pump therapy is clearly the most expensive therapeutic option; portable pump therapy is intermediate in expense, and conventional therapy is least expensive. Continuous intravenous or intraperitoneal delivery by implantable pump may provide superior metabolic control with fewer episodes of hypoglycemia. If such control retards the development of late complications, the additional cost of pump therapy will provide a favorable benefit-tocost ratio when weighed against the economic impact of diabetic complications. This content is only available as a PDF. © American Society of Clinical Pathologists
Takes, Peter, A.;Rinker,, Linda;Krug, Robert, D.
doi: 10.1093/labmed/23.10.658pmid: N/A
Abstract The ACCUSPIN (Sigma Diagnostics) and the LeucoPREP (Becton Dickinson) barrier methods for mononuclear cell separation were analyzed using density gradient centrifugation. Peripheral blood samples from healthy individuals and from those who tested positive for human immunodeficiency virus (HIV) were processed in parallel using both techniques and evaluated for total and percentage of mononuclear cell recovery. The ACCUSPIN method recovered more cells than the LeucoPREP method in 18 of 19 samples from healthy individuals. Specimens isolated with ACCUSPIN tubes also yielded 25% to 40% more cells than those isolated with LeucoPREP tubes. Similar results were obtained with blood samples from patients who tested HIV-positive. This content is only available as a PDF. Author notes Dr Takes is now with Sigma Immunochemicals, St Louis, and Ms Rinker is now with Celx, Seattle. © American Society of Clinical Pathologists
Johnston, Anne, M.;Kober,, Marie;Callaway, Thomas, H.
doi: 10.1093/labmed/23.10.663pmid: N/A
Abstract The authors evaluated the usefulness of Lyme disease western blots to supplement enzyme immunoassay (EIA) results in a clinical reference laboratory setting. Results from western blots suggested that a significant number of the EIA results were potentially false-positive as well as false-negative. The magnitude of EIA indexes and the positivity of western blots did not correlate. This content is only available as a PDF. © American Society of Clinical Pathologists
Goyzueta, Federico, G.;Billett, Henny, H.
doi: 10.1093/labmed/23.10.667pmid: N/A
Abstract To evaluate the performance of the automated Coag-A-Mate sampler, we compared the blood coagulation test results from this positive displacement dispenser with results from manual pipetting performed by medical technologists. More than 200 samples from patients were tested for prothrombin time (PT) and partial thromboplastin time (PTT) using both techniques. The PT (r=0.998) correlated well with the PTT (0.988). Test results showed that the coefficient of variation (CV) of the manual method and sampler methods are comparable for the PT (0.43% and 0.47%, respectively) and for the PTT (1.16% and 1.06%, respectively). Because the Coag-A-Mate sampler is automated, it frees the technologist to perform other tasks. The laboratory can perform singlet coagulation testing because the sampler’s CV is low enough to meet the standards of accreditation agencies. This content is only available as a PDF. © American Society of Clinical Pathologists
doi: 10.1093/labmed/23.10.671pmid: N/A
Article PDF first page preview Close This content is only available as a PDF. © American Society of Clinical Pathologists
doi: 10.1093/labmed/23.10.680pmid: N/A
Article PDF first page preview Close This content is only available as a PDF. © American Society of Clinical Pathologists
doi: 10.1093/labmed/23.10.686pmid: N/A
Article PDF first page preview Close This content is only available as a PDF. © American Society of Clinical Pathologists
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