Investigative Radiology

FRIEDLAND, ROBERT P.

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The authors propose that “undershoot”is caused by decreased oxygen content in venous blood compared with the preactivation level and may reflect increased extraction of oxygen as a result of glycolytic metabolism. The absence of “undershoot” after longer stimulation suggests a gradual shift from uncoupling between regional cerebral blood flow and oxygen consumption toward a steady state.

MEHTA, BHARAT A.

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Routine administration of gadolinium does not appear to be of benefit in imaging patients with complex partial seizures who are otherwise neurologically normal.

FELIX, ROLAND

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The usefulness of SNR and CNR analysis on MRI for the differentiation of malignant skin tumors from benign skin tumors of the melanin-containing system is limited. Clinical and histologic examinations are, further, the important step in evaluation of melanin-containing skin tumors.

WOLF, KARL J.

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Because of the higher CT attenuation of gadolinium compared with that of iodine, the neutral macrocyclic chelate gadobutrol is a more effective contrast agent than iopromide for CT at lower doses of the imaging atom.

HORSMAN, ANTHONY

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Dynamic scanning proved essential for the detection and differential diagnosis of local tumor recurrence. Pharmacokinetic analysis of Gd-DTPA uptake can be used to produce parametric images that retain the spatial resolution of the original images while providing additional information about lesion permeability and vascularity, and helping to avoid the observer variability associated with ROI analysis.

KURNIK, PETER B.

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Formulations of diatrizoate that minimize calcium binding are advocated for cardiac angiography when using high osmolality contrast media. The more detrimental effects that calcium binding has on myocardial function and cardiac conduction may lead to the higher incidence of complications.

HAWKINS, RANDALL

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It is possible to obtain a quantitative understanding of changes in blood oxygenation and to relate these changes to the observed dynamics of magnetic resonance signal change in the setting of functional stimulation.

TOVAR, MARIA C.

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Our results suggest that iohexol offers good radiologic efficacy and excellent systemic and local tolerance in small bowel obstruction.

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