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Bagot, Sarah; Pélissier, Léna; Pereira, Bruno; Chanséaume Bussiere, Emilie; Duclos, Martine; Dulloo, Abdul; Miles‐Chan, Jennifer; Charlot, Keyne; Boirie, Yves; Thivel, David; Isacco, Laurie
doi: 10.1111/obr.13658
Sundbom, Magnus; Näslund, Ingmar; Ottosson, Johan; Stenberg, Erik; Näslund, Erik
doi: 10.1111/obr.13662pmid: 37962040
In 2007, the Scandinavian Obesity Surgery Registry (SOReg) was started by the profession to monitor the results of bariatric surgery and to provide a high‐quality database for research. In the end of August 2023, SOReg contains 88,379 patients (body mass index [BMI] 41.7 kg/m2, 41.2 years, 77.1% females, gastric bypass 76.8%). In this narrative review, we demonstrate that preoperative weight loss is of value and that the laparoscopic double omega‐loop technique is highly suitable for gastric bypass. Closing the mesenteric openings is, however, important. Swedish bariatric surgery has low mortality, and our results are comparative to those of other countries. Significant long‐term improvements are found in common obesity‐related diseases such as diabetes, hypertension, and sleep apnea. Furthermore, the risk for cardiac failure and major adverse cardiovascular events is significantly reduced. Pregnancy‐related outcomes are also improved. Gastric bypass results in significant improvements in quality of life and seems to be cost saving. We have revealed that low socioeconomic status is associated with reduced chance of undergoing bariatric surgery and inferior outcomes. Of note, we have performed several randomized clinical trials within the registry database. In conclusion, high‐quality national registry databases, such as SOReg, are important for maintaining high‐quality care and present a platform for extensive research.
D'Cruz, Abhigale F. L.; D'Souza, Ninoshka J.; Downing, Katherine L.; Smith, Cynthia; Sciberras, Emma; Hesketh, Kylie D.
doi: 10.1111/obr.13657pmid: 38049177
Physical activity and self‐regulation are important predictors of pediatric overweight and obesity. Young children (0–5 years) with lower physical activity levels and poorer self‐regulation skills are at greater risk for overweight. Despite growing evidence that the two constructs are interrelated, their association remains unclear in young children. This review systematically summarized associations between physical activity and self‐regulation in early childhood and explored the directionality of associations. Searches were run in six electronic databases. Forty‐seven papers met inclusion criteria. Only three studies investigated all three domains of self‐regulation (behavioral, cognitive, and emotional). Overall, findings were inconclusive; studies reported weak to moderate positive associations (n = 17), inverse associations (n = 5), mixed associations (n = 15), null association (n = 2), and negative (n = 1) between physical activity and self‐regulation. Compared with the emotional and cognitive domains, physical activity was most consistently positively associated with behavioral self‐regulation. Only one study assessed bidirectional associations, reporting a positive association. The three studies that included global self‐regulation showed contradicting findings. There is some evidence that physical activity dose and sex potentially confound these associations; however, further research is needed given the paucity of studies. This review highlights the need for more in‐depth investigation of the complex association between physical activity and global self‐regulation.
Iqbal, Junaid; Wu, Hui‐Xuan; Nawaz, Muhammad Asad; Jiang, Hong‐Li; Xu, Shi‐Na; Huang, Bi‐Ling; Li, Long; Cai, Jun‐Min; Zhou, Hou‐De
doi: 10.1111/obr.13656pmid: 37904643
Studies have reported inconsistent results about the risk of incident chronic kidney disease (CKD) in people with metabolically healthy obesity (MHO). We designed this systematic review and meta‐analysis to evaluate the risk of developing CKD in people with MHO and metabolically unhealthy normal weight (MUNW). We used a predefined search strategy to retrieve eligible studies from multiple databases up to June 20, 2022. Random‐effects model meta‐analyses were implied to estimate the overall hazard ratio (HR) of incident CKD in obesity phenotypes. Eight prospective cohort studies, including approximately 5 million participants with a median follow‐up ranging between 3 and 14 years, were included in this meta‐analysis. Compared to the metabolically healthy normal weight (MHNW), the mean differences in cardiometabolic and renal risk factors in MHO, MUNW, and metabolically unhealthy obesity (MUO) were evaluated with overall HR of 1.42, 1.49, and 1.84, respectively. Compared to MHNW, the mean estimated glomerular filtration rate (eGFR) and high‐density lipoprotein (HDL) were significantly lower, and low‐density lipoprotein (LDL), blood pressure, blood glucose, and triglycerides were higher in MHO and MUNW. In conclusion, MHO and MUNW are not benign conditions and pose a higher risk for incident CKD. Obesity, whether in the presence or absence of metabolic health, is a risk factor for CKD.
Yu, Hongbiao; Chen, Ling; Zhang, Yulin
doi: 10.1111/obr.13653pmid: 37880747
Several studies have investigated a link between maternal preconception body mass index, gestational weight gain (GWG), and the risk of childhood allergic diseases, but the conclusions of these studies were inconsistent. This review aimed to evaluate the relationship based on existing studies. We eventually included 18 cohort studies. The findings indicated that both maternal preconception overweight or obesity increased the risk of childhood wheezing (overweight: risk ratio (RR) 1.09, 95% confidence interval (CI) 1.04–1.15; obesity: RR 1.24, 95% CI 1.12–1.38) and asthma (overweight: RR 1.18, 95% CI 1.05–1.32; obesity: RR 1.34, 95% CI 1.13–1.58), and the risk of childhood wheezing increased with continuous prepregnancy BMI changes (per 5 kg/m2 increase) (RR 1.10, 95% CI 1.05–1.15). Preconception underweight may elevate the risk of childhood eczema ever (RR 1.05, 95% CI 1.02–1.09) and current eczema (RR 1.20, 95% CI 1.05–1.37), and preconception overweight may reduce the risk of childhood eczema ever (RR 0.98, 95% CI 0.96–0.99). No statistically significant association between GWG and the risk of allergic diseases in children was found. Preconception weight management is encouraged for the prevention of allergic diseases in children.
Tan, Michelle M. C.; Barbosa, Matheus G.; Pinho, Pedro J. M. R.; Assefa, Esubalew; Keinert, Ana Á. M.; Hanlon, Charlotte; Barrett, Barbara; Dregan, Alexandru; Su, Tin Tin; Mohan, Devi; Ferri, Cleusa; Muniz‐Terrera, Graciela; Prina, Matthew; ,
doi: 10.1111/obr.13661pmid: 38105610
Davis, Corinne; Huggins, Catherine E.; Kleve, Sue; Leung, Gloria K. W.; Bonham, Maxine P.
doi: 10.1111/obr.13659pmid: 37985937
Shift workers have an increased risk of obesity and metabolic conditions. This mixed‐methods systematic literature review on night shift workers aimed to: (1) identify barriers/enablers of weight management; (2) examine effectiveness of weight management interventions; and (3) determine whether interventions addressed enablers/barriers. Six databases were searched, articles screened by title/abstract, followed by full‐text review, and quality assessment. Eligible qualitative studies documented experiences of behaviors related to weight change. Eligible quantitative studies were behavior change interventions with weight/body mass index outcomes. A thematic synthesis was undertaken for qualitative studies using the social‐ecological model (SEM). Interventions were synthesized narratively including: weight/body composition change; components mapped by behavior change taxonomy; and SEM. A synthesis was undertaken to identify if interventions addressed perceived enablers/barriers. Eight qualitative (n = 169 participants) and 12 quantitative studies (n = 1142 participants) were included. Barriers predominated discussions: intrapersonal (time, fatigue, stress); interpersonal (work routines/cultural norms); organizational (fatigue, lack of: routine, healthy food options, breaks/predictable work); community (lack of healthy food options). The primary outcome for interventions was not weight loss and most did not address many identified enablers/barriers. One intervention reported a clinically significant weight loss result. Weight loss interventions that address barriers/enablers at multiple SEM levels are needed.
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Depending on the nature of their sports, athletes may be engaged in successive weight loss (WL) and regain, conducing to “weight cycling.” The aims of this paper were to systematically (and meta‐analytically when possible) analyze the post‐WL recovery of (i) body weight and (ii) fat mass; fat‐free mass; and performance and metabolic responses in weight cycling athletes (18–55 years old, body mass index < 30 kg.m−2). MEDLINE, Embase, and SPORTDiscus databases were explored. The quality and risk of bias of the 74 included studies were assessed using the quality assessment tool for quantitative studies. Thirty‐two studies were eligible for meta‐analyses. Whatever the type of sports or methods used to lose weight, post‐WL body weight does not seem affected compared with pre‐WL. While similar results are observed for fat‐free mass, strength sports athletes (also having longer WL and regain periods) do not seem to fully recover their initial fat mass (ES: −0.39, 95% CI: [−0.77; −0.00], p = 0.048, I2 = 0.0%). Although the methods used by athletes to achieve WL might prevent them from a potential post‐WL fat overshooting, further studies are needed to better understand WL episodes consequences on athletes' performance as well as short‐ and long‐term physical, metabolic, and mental health.
Multimorbidity—the coexistence of at least two chronic health conditions within the same individual—is an important global health challenge. In high‐income countries (HICs), multimorbidity is dominated by non‐communicable diseases (NCDs); whereas, the situation may be different in low‐ and middle‐income countries (LMICs), where chronic communicable diseases remain prominent. The aim of this systematic review was to identify determinants (including risk and protective factors) and potential mechanisms underlying multimorbidity from published longitudinal studies across diverse population‐based or community‐dwelling populations in LMICs. We systematically searched three electronic databases (Medline, Embase, and Global Health) using pre‐defined search terms and selection criteria, complemented by hand‐searching. All titles, abstracts, and full texts were independently screened by two reviewers from a pool of four researchers. Data extraction and reporting were according to Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines. Methodological quality and risk of bias assessment was performed using the Newcastle‐Ottawa Scale for cohort studies. Data were summarized using narrative synthesis. The search yielded 1782 records. Of the 52 full‐text articles included for review, 8 longitudinal population‐based studies were included for final data synthesis. Almost all studies were conducted in Asia, with only one from South America and none from Africa. All studies were published in the last decade, with half published in the year 2021. The definitions used for multimorbidity were heterogeneous, including 3–16 chronic conditions per study. The leading chronic conditions were heart disease, stroke, and diabetes, and there was a lack of consideration of mental health conditions (MHCs), infectious diseases, and undernutrition. Prospectively evaluated determinants included socio‐economic status, markers of social inequities, childhood adversity, lifestyle behaviors, obesity, dyslipidemia, and disability. This review revealed a paucity of evidence from LMICs and a geographical bias in the distribution of multimorbidity research. Longitudinal research into epidemiological aspects of multimorbidity is warranted to build up scientific evidence in regions beyond Asia. Such evidence can provide a detailed picture of disease development, with important implications for community, clinical, and interventions in LMICs. The heterogeneity in study designs, exposures, outcomes, and statistical methods observed in the present review calls for greater methodological standardisation while conducting epidemiological studies on multimorbidity. The limited evidence for MHCs, infectious diseases, and undernutrition as components of multimorbidity calls for a more comprehensive definition of multimorbidity globally.