journal article
LitStream Collection
A Sequential Model of Host Cell Killing and Phagocytosis by Entamoeba histolytica
Sateriale, Adam;Huston, Christopher D.
doi: 10.1155/2011/926706pmid: 21331284
The protozoan parasite <i>Entamoeba histolytica</i> is responsible for invasive intestinal and extraintestinal amebiasis. The virulence of <i>Entamoeba histolytica</i> is strongly correlated with the parasite's capacity to effectively kill and phagocytose host cells. The process by which host cells are killed and phagocytosed follows a sequential model of adherence, cell killing, initiation of phagocytosis, and engulfment. This paper presents recent advances in the cytolytic and phagocytic processes of <i>Entamoeba histolytica</i> in context of the sequential model.