TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 274, No. 36, Issue of September 3, pp. 25386 –25392, 1999 © 1999 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. NADH Shuttle System Regulates K Channel-dependent Pathway ATP Concentration Elevation in and Steps Distal to Cytosolic Ca Glucose-induced Insulin Secretion* (Received for publication, April 13, 1999) Kazuhiro Eto‡, Sechiko Suga§, Makoto Wakui§, Yoshiharu Tsubamoto‡, Yasuo Terauchi‡, Junko Taka‡, Shinichi Aizawa¶, Mitsuhiko Noda‡, Satoshi Kimura‡, Haruo Kasaii, and Takashi Kadowaki‡** From the ‡Department of Metabolic Diseases and iDepartment of Physiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan, §Department of Physiology, Hirosaki University School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan, and ¶Department of Morphogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University School of Medicine, 4-24-1 Kuhonji, Kumamoto 862, Japan The NADH shuttle system is composed of the glycerol ratio of ATP to ADP closes ATP-sensitive potassium (K ) ATP channels, which depolarizes the plasma membrane potential phosphate and malate-aspartate shuttles. We generated mice that lack mitochondrial glycerol-3-phosphate de- above a threshold, leading to Ca entry into the cytosol hydrogenase (mGPDH), a rate-limiting enzyme of the through activation of voltage-dependent Ca channels 
TI - NADH Shuttle System Regulates KATPChannel-dependent Pathway and Steps Distal to Cytosolic Ca2+ Concentration Elevation in Glucose-induced Insulin Secretion
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.274.36.25386
DA - 1999-09-01
UR - https://www.deepdyve.com/lp/unpaywall/nadh-shuttle-system-regulates-katpchannel-dependent-pathway-and-steps-08AxsnE8Qi
DP - DeepDyve
ER -