TY - JOUR
AU - Hagmar, Lars
AB - ORIGINAL ARTICLE Urinary Phthalate Metabolites and Biomarkers of Reproductive Function in Young Men * † * † * Bo A.G. Jo¨nsson, Jonas Richthoff, Lars Rylander, Aleksander Giwercman, and Lars Hagmar It is not yet possible to conclude whether phthalate exposure may Background: High exposure to phthalates, which are ubiquitous reflect a hazard for human male reproduction. contaminants, has been shown in animal studies to produce detri- mental effects on male reproductive functions. A recent study in (Epidemiology 2005;16: 487– 493) humans reported dose–response relations between low phthalate levels in urine and human semen parameters, which raises the question whether humans are more sensitive to phthalate exposure than animals. here are indications that the sperm density among men Methods: Urine, serum, and semen samples were collected from Tfrom the Western world may have deteriorated during the 234 young Swedish men at the time of their medical conscript 1,2 past decades. It has been suggested that this trend is due to examination. Semen volume, sperm concentration, and motility were measured, together with sperm chromatin integrity (sperm increasing fetal exposure to compounds with estrogenic or chromatin structure assay) and biochemical markers of epididymal antiandrogenic effects, so-called “endocrine-disrupting com- and prostatic function. We 
TI - Urinary Phthalate Metabolites and Biomarkers of Reproductive Function in Young Men
JF - Epidemiology
DO - 10.1097/01.ede.0000164555.19041.01
DA - 2005-07-01
UR - https://www.deepdyve.com/lp/wolters-kluwer-health/urinary-phthalate-metabolites-and-biomarkers-of-reproductive-function-0I0ghRQJdN
SP - 487
EP - 493
VL - 16
IS - 4
DP - DeepDyve
ER -