TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 273, No. 3, Issue of January 16, pp. 1794 –1801, 1998 © 1998 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. The XRCC4 Gene Product Is a Target for and Interacts with the DNA-dependent Protein Kinase* (Received for publication, May 30, 1997, and in revised form, October 10, 1997) Ray Leber‡§, Teresa W. Wise‡§, Ryushin Mizuta¶, and Katheryn Meek‡i** From the iHarold C. Simmons Arthritis Research Center, the ‡Department of Internal Medicine and Program in Immunology, University of Texas Southwestern Medical Center, Dallas, Texas 75235 and ¶The Center for Blood Research and Department of Genetics, Harvard University Medical School, Boston, Massachusetts 02115 The gene product of XRCC4 has been implicated in 1 and RAG 2) (3, 4) are directly responsible for initiation of the V(D)J recombination reaction (5– 8) together directing cleavage both V(D)J recombination and the more general process of double strand break repair (DSBR). To date its role in at the recombination signal sequence-coding juncture; whereas these processes is unknown. Here, we describe biochem- resolution of recombination intermediates also requires several ical characteristics of the murine XRCC4 protein. ubiquitously expressed DNA repair factors. Evidence linking XRCC4 
TI - The XRCC4 Gene Product Is a Target for and Interacts with the DNA-dependent Protein Kinase
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.273.3.1794
DA - 1998-01-01
UR - https://www.deepdyve.com/lp/unpaywall/the-xrcc4-gene-product-is-a-target-for-and-interacts-with-the-dna-0Lcg8hreDg
DP - DeepDyve
ER -