TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276, No. 50, Issue of December 14, pp. 47202–47211, 2001 © 2001 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Contrasting Effects of IG20 and Its Splice Isoforms, MADD and -induced Apoptosis and DENN-SV, on Tumor Necrosis Factor Activation of Caspase-8 and -3* Received for publication, May 26, 2001, and in revised form, August 30, 2001 Published, JBC Papers in Press, September 27, 2001, DOI 10.1074/jbc.M104835200 Adeeb M. Al-Zoubi‡, Elena V. Efimova‡, Shashi Kaithamana, Osvaldo Martinez, Mohammed El-Azami El-Idrissi, Rukiye E. Dogan, and Bellur S. Prabhakar§ From the Department of Microbiology and Immunology, University of Illinois, Chicago, Illinois 60612 We identified a novel cDNA (IG20) that is homolo- cellular signal transduction by a diverse array of cytoplasmic gous to cDNAs encoding a protein differentially ex- adaptor proteins. Some of these adaptor proteins contain a pressed in normal and neoplastic cells (DENN-SV) and death domain through which they interact with the cytoplas- human MADD (MAPK-activating death domain-con- mic death domain of TNFR1 (4 – 6). taining protein). Furthermore, we show that the above Previously, we and others identified some cDNAs that are variants most likely result from alternative splicing 
TI - Contrasting Effects of IG20 and Its Splice Isoforms, MADD and DENN-SV, on Tumor Necrosis Factor α-induced Apoptosis and Activation of Caspase-8 and -3
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m104835200
DA - 2001-12-01
UR - https://www.deepdyve.com/lp/unpaywall/contrasting-effects-of-ig20-and-its-splice-isoforms-madd-and-denn-sv-0QcIb3FQNN
DP - DeepDyve
ER -