TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 278, No. 30, Issue of July 25, pp. 27658–27662, 2003 © 2003 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Enrichment for Histone H3 Lysine 9 Methylation at Alu Repeats in Human Cells* Received for publication, April 17, 2003, and in revised form, April 28, 2003 Published, JBC Papers in Press, April 30, 2003, DOI 10.1074/jbc.M304072200 Yutaka Kondo‡ and Jean-Pierre J. Issa§ From the Department of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030 modifications influence transcription by affecting chromatin The aim of this study was to identify in human cells 9 9 common targets of histone H3 lysine 9 (H3-Lys ) methy- structure. Recent studies have shown that methylation at Lys lation, a modification that is generally associated with on histone H3 is a marker of heterochromatin and is specifi- gene silencing. After chromatin immunoprecipitation cally associated with inactivation of gene expression (5). H3- using an H3-Lys methylated antibody, we cloned the Lys methylation is enriched on the inactive X chromosome in recovered DNA and sequenced 47 independent clones. women (6) and at loci silenced in cancer (7–9). Beyond this, the Of these, 
TI - Enrichment for Histone H3 Lysine 9 Methylation at Alu Repeats in Human Cells
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m304072200
DA - 2003-07-01
UR - https://www.deepdyve.com/lp/unpaywall/enrichment-for-histone-h3-lysine-9-methylation-at-alu-repeats-in-human-2Cb2UDssi1
DP - DeepDyve
ER -