TY - JOUR AU - AB - MINI REVIEW published: 31 October 2017 doi: 10.3389/fncir.2017.00086 From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits Ying Yang and Jian-Zhi Wang* Department of Pathophysiology, School of Basic Medicine and the Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Emotion influences various cognitive processes, including learning and memory. The amygdala is specialized for input and processing of emotion, while the hippocampus is essential for declarative or episodic memory. During emotional reactions, these two brain regions interact to translate the emotion into particular outcomes. Here, we briefly introduce the anatomy and functions of amygdala and hippocampus, and then present behavioral, electrophysiological, optogenetic and biochemical evidence from recent studies to illustrate how amygdala and hippocampus work synergistically to form long-term memory. With recent technological advances, the causal investigations of specific neural circuit between amygdala and hippocampus will help us understand the brain mechanisms of emotion-regulated memories and improve clinical treatment of emotion-associated memory disorders in patients. Keywords: emotion, memory, amygdala, hippocampus, neural circuits INTRODUCTION Over the past half century, it is increasingly recognized that memories are governed by distinct Edited by: and TI - From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits JF - Frontiers in Neural Circuits DO - 10.3389/fncir.2017.00086 DA - 2017-10-31 UR - https://www.deepdyve.com/lp/unpaywall/from-structure-to-behavior-in-basolateral-amygdala-hippocampus-36VEmNIO8W DP - DeepDyve ER -