TY - JOUR AU - Campbell, C A AB - Natural selection is simply the process of differential reproduction of organisms differing in genetic constitution. Differential reproduction may be predicated of an individual, relative to other individuals of the same population; of a genotype, relative to other genotypes in the population; and of an allele, relative to alternative alleles at the same locus. One may also speak of the differential reproduction of populations, a process usually described as "group selection." The population genet­ icist is primarily concerned with changes in allelic and genotypic frequencies in populations. Carriers of a given allele may contribute more progeny to the following generation than carriers of alternative alleles; the former allele is then said to be favored by natural selection and will increase in frequency in the population through the generations. Alleles exist in organisms in combination with other alleles at different loci; in diploid organisms they exist also in combinations with alleles at the same locus. The reproductive performance of the carriers of a given allele is likely to be affected by the alleles with which it is associated. It is, therefore, most informative to study the reproductive efficiency of carriers of given genotypes. In diploid organisms, differential reproduction is generally TI - Frequency-Dependent Selection JF - Annual Review of Ecology, Evolution, and Systematics DO - 10.1146/annurev.es.05.110174.000555 DA - 1974-11-01 UR - https://www.deepdyve.com/lp/annual-reviews/frequency-dependent-selection-4CKtN2Q9P6 SP - 115 EP - 138 VL - 5 IS - 1 DP - DeepDyve ER -