TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 272, No. 50, Issue of December 12, pp. 31570 –31575, 1997 © 1997 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Role of Asymmetric Phosphate Neutralization in DNA Bending by PU.1* (Received for publication, August 11, 1997, and in revised form, September 29, 1997) Juliane K. Strauss-Soukup‡§ and L. James Maher, III§¶ From the ‡Department of Biochemistry and Molecular Biology and Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska 68198 and the §Department of Biochemistry and Molecular Biology, Mayo Foundation, Rochester, Minnesota 55905 The PU.1 transcription factor is a member of the Ets induces ;20° of bending toward the neutralized surface (3). family of DNA binding proteins. PU.1 binds to DNA via a Qualitatively similar DNA bending is observed if cations are loop-helix-loop domain and functions in the differentia- tethered to the double helix (4, 5). tion of hematopoietic cells. The structure of a PU.1-DNA Crystallographic and gel electrophoresis studies of DNA complex was recently reported (Kodandapani, R., Pio, bending proteins also suggest that neutralization of phosphate F., Ni, C.-Z., Piccialli, G., Klemsz, M., McKercher, S., charge is a possible 
TI - Role of Asymmetric Phosphate Neutralization in DNA Bending by PU.1
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.272.50.31570
DA - 1997-12-01
UR - https://www.deepdyve.com/lp/unpaywall/role-of-asymmetric-phosphate-neutralization-in-dna-bending-by-pu-1-5PRE9gBKLu
DP - DeepDyve
ER -