TY - JOUR
AU1 - Friedrich, Reinhard E
AU2 - Nuding, Michael A
AB - Optic pathway glioma (OPG) is a rare neoplasm and a defining feature of neurofibromatosis type 1 (NF1), a tumor suppressor genetic disorder. OPG predominantly arises during childhood. In contrast to sporadic OPG, this neoplasm frequently appears to show a more favorable course. Outcome appears to depend on localization of tumor; however, the correlation of imaging findings and visual acuity is in general low. Treatment for symptomatic OPG is not well standardized. Furthermore, determination of visual acuity as the most important parameter of follow-up control is often difficult to determine, particularly in children. Focal abnormal signal intensity (FASI) is a characteristic finding on magnetic resonance imaging (MRI) of NF1 patients. The aim of this study was to evaluate clinical and imaging findings of NF1 patients affected with OPG.
TI - Optic Pathway Glioma and Cerebral Focal Abnormal Signal Intensity in Patients with Neurofibromatosis Type 1: Characteristics, Treatment Choices and Follow-up in 134 Affected Individuals and a Brief Review of the Literature.
JF - Anticancer research
DA - 2017-01-25
UR - https://www.deepdyve.com/lp/pubmed/optic-pathway-glioma-and-cerebral-focal-abnormal-signal-intensity-in-624ekIs96U
SP - 4095
EP - 4121
VL - 36
IS - 8
DP - DeepDyve
ER -