TY - JOUR
AU1 - Babben, Steve
AU2 - Schliephake, Edgar
AU3 - Janitza, Philipp
AU4 - Berner, Thomas
AU5 - Keilwagen, Jens
AU6 - Koch, Michael
AU7 - Arana-Ceballos, Fernando
AU8 - Templer, Sven
AU9 - Chesnokov, Yuriy
AU1 - Pshenichnikova, Tatyana
AU1 - Schondelmaier, Jörg
AU1 - Börner, Andreas
AU1 - Pillen, Klaus
AU1 - Ordon, Frank
AU1 - Perovic, Dragan
AB - Background: Understanding the genetic basis of frost tolerance (FT) in wheat (Triticum aestivum L.) is essential for preventing yield losses caused by frost due to cellular damage, dehydration and reduced metabolism. FT is a complex trait regulated by a number of genes and several gene families. Availability of the wheat genomic sequence opens new opportunities for exploring candidate genes diversity for FT. Therefore, the objectives of this study were to identity SNPs and insertion-deletion (indels) in genes known to be involved in frost tolerance and to perform association genetics analysis of respective SNPs and indels on FT. Results: Here we report on the sequence analysis of 19 candidate genes for FT in wheat assembled using the Chinese Spring IWGSC RefSeq v1.0. Out of these, the tandem duplicated C-repeat binding factors (CBF), i.e. CBF-A3, CBF-A5, CBF-A10, CBF-A13, CBF-A14, CBF-A15, CBF-A18, the vernalisation response gene VRN-A1, VRN-B3, the photoperiod response genes PPD-B1 and PPD-D1 revealed association to FT in 235 wheat cultivars. Within six genes (CBF-A3, CBF-A15, VRN-A1, VRN-B3, PPD-B1 and PPD-D1) amino acid (AA) substitutions in important protein domains were identified. The amino acid substitution effect in VRN-A1 on FT was confirmed and new AA substitutions in CBF-A3, CBF-A15, VRN-B3, 
TI - Association genetics studies on frost tolerance in wheat (Triticum aestivum L.) reveal new highly conserved amino acid substitutions in CBF-A3, CBF-A15, VRN3 and PPD1 genes
JF - BMC Genomics
DO - 10.1186/s12864-018-4795-6
DA - 2018-05-29
UR - https://www.deepdyve.com/lp/springer-journals/association-genetics-studies-on-frost-tolerance-in-wheat-triticum-66GcZXXyBh
SP - 1
EP - 24
VL - 19
IS - 1
DP - DeepDyve
ER -