TY - JOUR
AU1 - Iizuka, Kei
AU2 - Nishinaka, Tomohiro
AU3 - Ichihara, Yuki
AU4 - Miyamoto, Takuma
AU5 - Yamazaki, Kenji
AB - Aortic valve regurgitation (AR) is a critical complication during circulatory support with a left ventricular assist device (LVAD). The time-course of AR and related factors, including outflow graft anastomosis site design, were investigated. Twenty-three patients who had continuous-flow LVAD implantation and were supported for more than 6 months were investigated. AR grade (none, 0; trivial, 0.5; mild, 1; mild-moderate, 1.5; moderate, 2; moderate-severe, 2.5; severe, 3) and aortic valve opening were evaluated with echocardiography. Computed tomography was performed to all the patients postoperatively. The angle of the outflow graft to the aorta (O-A angle, parallel 0; tangent 90°, 0–180°), aortic diameter at the anastomosis site, sino-tubular junction (STJ) diameter, distance between the STJ and the anastomosis site, and distance between the anastomosis site and the brachiocephalic artery were measured. The patients’ age was 38 ± 11 years. Support duration was 686 ± 354 days. Mean AR grade after continuous-flow LVAD implantation was increased to around mild and was maintained thereafter. No patient needed any intervention to the aortic valve. The aortic valves of 82.6% of patients were closed continuously. The O-A angle (83 ± 14) was positively correlated with maximum AR grade (p = 0.0095). The O-A angle was significantly smaller in patients with maximum AR grade of 1 or less (77 ± 9°) than in those with 1.5 or greater (94 ± 15°, p = 0.021). The other CT measurements had no correlation with AR grade. In conclusion, the O-A angle was correlated with AR grade progression. The O-A angle appears to be one of the important factors related to AR under continuous-flow LVAD support.
TI - Outflow graft anastomosis site design could be correlated to aortic valve regurgitation under left ventricular assist device support
JF - Journal of Artificial Organs
DO - 10.1007/s10047-017-1006-1
DA - 2017-11-21
UR - https://www.deepdyve.com/lp/springer-journals/outflow-graft-anastomosis-site-design-could-be-correlated-to-aortic-6N0r66lzct
SP - 150
EP - 155
VL - 21
IS - 2
DP - DeepDyve
ER -