TY - JOUR AU1 - Epstein, Robert S. AB - ORIGINAL ARTICLE Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost Michael C. Sokol, MD, MS, Kimberly A. McGuigan, PhD, Robert R. Verbrugge, PhD, and Robert S. Epstein, MD, MS Conclusions: For some chronic conditions, increased drug utiliza- Objective: The objective of this study was to evaluate the impact of tion can provide a net economic return when it is driven by medication adherence on healthcare utilization and cost for 4 improved adherence with guidelines-based therapy. chronic conditions that are major drivers of drug spending: diabetes, Key Words: adherence, drug utilization, healthcare costs, hypertension, hypercholesterolemia, and congestive heart failure. hospitalization, pharmaceutical care Research Design: The authors conducted a retrospective cohort observation of patients who were continuously enrolled in medical (Med Care 2005;43: 521–530) and prescription benefit plans from June 1997 through May 1999. Patients were identified for disease-specific analysis based on claims for outpatient, emergency room, or inpatient services during the first 12 months of the study. Using an integrated analysis of administra- tive claims data, medical and drug utilization were measured during rescription drug expenditures are the fastest growing the 12-month period after patient identification. Medication adher- 1,2 Pcomponent of healthcare costs in the United States. ence TI - Impact of Medication Adherence on Hospitalization Risk and Healthcare Cost JF - Medical Care DO - 10.1097/01.mlr.0000163641.86870.af DA - 2005-06-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/impact-of-medication-adherence-on-hospitalization-risk-and-healthcare-6dtHVtFSSA SP - 521 EP - 530 VL - 43 IS - 6 DP - DeepDyve ER -