TY - JOUR
AU - 
AB - MINI REVIEW ARTICLE published: 21 December 2011 doi: 10.3389/fmicb.2011.00258 Structural features of antiviral APOBEC3 proteins are linked to their functional activities 1,2 1 1,3 Shingo Kitamura , Hirotaka Ode and Yasumasa Iwatani * Laboratory of Infectious Diseases, Department of Infectious Diseases and Immunology, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan Department of Biotechnology, Graduate School of Engineering, Nagoya University, Nagoya, Japan Department of AIDS Research, Graduate School of Medicine, Nagoya University, Nagoya, Japan Edited by: Human APOBEC3 (A3) proteins are cellular cytidine deaminases that potently restrict the Akio Adachi, The University of replication of retroviruses by hypermutating viral cDNA and/or inhibiting reverse transcrip- Tokushima Graduate School, Japan tion. There are seven members of this family including A3A, B, C, DE, F, G, and H, all Reviewed by: encoded in a tandem array on human chromosome 22. A3F and A3G are the most potent Youichi Suzuki, National University of Singapore, Singapore inhibitors of HIV-1, but only in the absence of the virus-encoded protein, Vif. HIV-1 utilizes Kenzo Tokunaga, National Institute of Vif to abrogate A3 functions in the producer cells. More specifically, Vif, serving as a sub- Infectious Diseases, Japan strate receptor, facilitates ubiquitination of A3 
TI - Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities
JF - Frontiers in Microbiology
DO - 10.3389/fmicb.2011.00258
DA - 2011-01-01
UR - https://www.deepdyve.com/lp/unpaywall/structural-features-of-antiviral-apobec3-proteins-are-linked-to-their-7fQaF5lEBK
DP - DeepDyve
ER -