TY - JOUR AU - Karp, Joel S AB - Fully three-dimensional (3-D) reconstruction algorithms have the potential to better utilize PET data acquired in true 3-D acquisition modes, as compared to 2-D approaches involving data reduction through rebinning procedures followed by a 2-D or 2.5-D reconstruction. Our previous studies, involving simulated and real phantom data from PET scanners working purely in 3-D acquisition mode, showed that the fully 3-D reconstruction approaches bring appreciable improvement on physical measures and visual image quality as well. Reconstruction procedures utilized in those studies were based upon the row action maximum likelihood algorithm (RAMLA) implemented on our clinical scanners. The purpose of this study was to investigate if the fully 3-D RAMLA reconstruction software brings an appreciable improvement in clinical image quality and reader confidence. TI - Clinical validation of fully 3-D versus 2.5-D RAMLA reconstruction on the Philips-ADAC CPET PET scanner. JF - Nuclear medicine communications DO - 10.1097/00006231-200411000-00006 DA - 2005-03-22 UR - https://www.deepdyve.com/lp/pubmed/clinical-validation-of-fully-3-d-versus-2-5-d-ramla-reconstruction-on-8QmVETnuzg SP - 1103 EP - 7 VL - 25 IS - 11 DP - DeepDyve ER -