TY - JOUR
AU1 - Walter, Edward James
AU2 - Hanna-Jumma, Sameer
AU3 - Carraretto, Mike
AU4 - Forni, Lui
AB - There are numerous causes of a raised core temperature. A fever occurring in sepsis may be associated with a survival benefit. However, this is not the case for non-infective triggers. Where heat generation exceeds heat loss and the core temperature rises above that set by the hypothalamus, a combination of cellular, local, organ-specific, and systemic effects occurs and puts the individual at risk of both short-term and long-term dysfunction which, if severe or sustained, may lead to death. This narrative review is part of a series that will outline the pathophysiology of pyrogenic and non-pyrogenic fever, concentrating primarily on the pathophysiology of non-septic causes.
TI - The pathophysiological basis and consequences of fever
JF - Critical Care
DO - 10.1186/s13054-016-1375-5
DA - 2016-07-14
UR - https://www.deepdyve.com/lp/pubmed-central/the-pathophysiological-basis-and-consequences-of-fever-8pgW3u8uY9
VL - 20
IS - 
DP - DeepDyve
ER -