TY - JOUR AU1 - Caporaso, J Gregory AU2 - Kuczynski, Justin AU3 - Stombaugh, Jesse AU4 - Bittinger, Kyle AU5 - Bushman, Frederic D AU6 - Costello, Elizabeth K AU7 - Fierer, Noah AU8 - Peña, Antonio Gonzalez AU9 - Goodrich, Julia K AU1 - Gordon, Jeffrey I AU1 - Huttley, Gavin A AU1 - Kelley, Scott T AU1 - Knights, Dan AU1 - Koenig, Jeremy E AU1 - Ley, Ruth E AU1 - Lozupone, Catherine A AU1 - McDonald, Daniel AU1 - Muegge, Brian D AU1 - Pirrung, Meg AU2 - Reeder, Jens AU2 - Sevinsky, Joel R AU2 - Turnbaugh, Peter J AU2 - Walters, William A AU2 - Widmann, Jeremy AU2 - Yatsunenko, Tanya AU2 - Zaneveld, Jesse AU2 - Knight, Rob AB - correspond ence line built using the PyCogent toolkit , to address the problem of QIIME allows analysis of high- taking sequencing data from raw sequences to interpretation and database deposition. QIIME, available at http://qiime.sourceforge. throughput community sequencing data net/, supports a wide range of microbial community analyses and To the Editor: High-throughput sequencing is revolutionizing visualizations that have been central to several recent high-pro- microbial ecology studies. Efforts like the Human Microbiome file studies, including network analysis, histograms of within- or 1 2 Projects and the US National Ecological Observatory Network are between-sample diversity and analysis of whether ‘core’ sets of helping us to understand the role of microbial diversity in habitats organisms are consistently represented in certain habitats. QIIME within our own bodies and throughout the planet. also provides graphical displays that allow users to interact with the Pyrosequencing using error-correcting, sample-specific barcodes data. Our implementation is highly modular and makes extensive allows hundreds of communities to be analyzed simultaneously in use of unit testing to ensure the accuracy of results. This modularity multiplex . Integrating information from thousands of samples, allows alternative components for functionalities such as choosing including those obtained from time series, can reveal large-scale TI - QIIME allows analysis of high-throughput community sequencing data JF - Nature Methods DO - 10.1038/nmeth.f.303 DA - 2010-04-11 UR - https://www.deepdyve.com/lp/springer-journals/qiime-allows-analysis-of-high-throughput-community-sequencing-data-8qMOUN7nvQ SP - 335 EP - 336 VL - 7 IS - 5 DP - DeepDyve ER -