TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 272, No. 47, Issue of November 21, pp. 29742–29751, 1997 © 1997 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Molecular Cloning and Cell Cycle-dependent Expression of Mammalian CRM1, a Protein Involved in Nuclear Export of Proteins* (Received for publication, May 27, 1997, and in revised form, August 27, 1997) Nobuaki Kudo, Saadi Khochbin‡, Kazunori Nishi§, Kazuaki Kitano§, Mitsuhiro Yanagida¶, Minoru Yoshidai, and Sueharu Horinouchi From the Department of Biotechnology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku Tokyo 113, ‡INSERM U309, Institut Albert Bonniot, Faculte de Medecine, La Tronche, France, the §Pharmaceutical Discovery Research Division, Takeda Chemical Industries, Ltd., Tsukuba, Ibaraki 300-42, and the ¶Department of Biophysics, Faculty of Science, Kyoto University, Sakyo-ku, Kyoto 606-01, Japan Crm1 of Schizosaccharomyces pombe, a nuclear pro- The structure of eukaryotic chromatin, which is folded and tein essential for proliferation and chromosome region packed into the nucleus, dynamically changes during the cell maintenance, is a possible target of leptomycin B, an cycle. In the M phase, the chromatin is highly condensed to antifungal and antitumor antibiotic with cell cycle-ar- become mitotic chromosomes with higher order structures. The 
TI - Molecular Cloning and Cell Cycle-dependent Expression of Mammalian CRM1, a Protein Involved in Nuclear Export of Proteins
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.272.47.29742
DA - 1997-11-01
UR - https://www.deepdyve.com/lp/unpaywall/molecular-cloning-and-cell-cycle-dependent-expression-of-mammalian-9GwRyEjhh3
DP - DeepDyve
ER -