TY - JOUR AU - Lalande, Marc AB - © 1998 Nature Publishing Group http://www.nature.com/naturegenetics correspondence peutic levels and should be life-long and 2 associated virus·mediated transduction in the Carol H. Miao , Richard 0. Snyder , skeletal muscle of adult immunocompetent mice . 1 1 suitable for the treatment of genetic dis­ David B. Schowalter , Gijsbert A. Patijn , Hum. Gene Ther. 8, 1891-1900 (1997). eases. The mechanism which results in a 6. Kessler, P.O. et a/. Proc. Nat/. Acad. Sci. USA 93, Brian Donahue , Brian Winther1, 14082-14087 (1996). relatively small percentage of hepatocytes & Mark A. Kay 7. Fisher, K.J. eta/. Nature Med. 3, 306-312 (1997). containing multiple rAAV genomes will Division of Medical Genetics Box 351720, 7 705 8. Herzog, R.W. eta/. Proc. Nat/. Acad. Sci. USA 94, 5804--5809 (1997) . NE Pacific St, University of Washington, Seattle, require further study. Perhaps a threshold 9. Flannery, J.G. et a/. Proc. Nat/. Acad. Sci. USA 94, Washington 98195, USA. 2Ce/l Genesys, Foster amount of vector genome and/or the pres­ 6916-6921 (1997). City, California, USA. Correspondence should 10. Xiao, X .. Li, J. & Samulski, R.J. 1. Virology 70, ence of an as yet unknown cellular milieu 8091H1108 (1996). be addressed to M.A.K. e-mail: is TI - An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript JF - Nature Genetics DO - 10.1038/ng0598-15 DA - 1998-05-01 UR - https://www.deepdyve.com/lp/springer-journals/an-imprinted-antisense-rna-overlaps-ube3a-and-a-second-maternally-AN0IvHsA2e SP - 15 EP - 16 VL - 19 IS - 1 DP - DeepDyve ER -