TY - JOUR
AU - Wang, Pengyuan
AB - Post-transcriptional regulation of RNAs is critical to the diverse range of cellular processes. The volume of functional genomic data focusing on post-transcriptional regulation logics continues to grow in recent years. In the current database version, POSTAR2 (http://lulab.life.tsinghua.edu.cn/postar), we included the following new features and data: updated ∼500 CLIP-seq datasets (∼1200 CLIP-seq datasets in total) from six species, including human, mouse, fly, worm, Arabidopsis and yeast; added a new module ‘Translatome’, which is derived from Ribo-seq datasets and contains ∼36 million open reading frames (ORFs) in the genomes from the six species; updated and unified post-transcriptional regulation and variation data. Finally, we improved web interfaces for searching and visualizing protein–RNA interactions with multi-layer information. Meanwhile, we also merged our CLIPdb database into POSTAR2. POSTAR2 will help researchers investigate the post-transcriptional regulatory logics coordinated by RNA-binding proteins and translational landscape of cellular RNAs.
TI - POSTAR2: deciphering the post-transcriptional regulatory logics
JF - Nucleic Acids Research
DO - 10.1093/nar/gky830
DA - 2019-01-08
UR - https://www.deepdyve.com/lp/oxford-university-press/postar2-deciphering-the-post-transcriptional-regulatory-logics-AWXgnESL5H
SP - D203
EP - D211
VL - 47
IS - D1
DP - DeepDyve
ER -