TY - JOUR
AU - 
AB - Vol. 270, No. 10, Issue of Msrch 10, pp. 5631-5635, 1995 THE JOURNAL OF BIOLOGICAL CHEMISTRY Printed in U.S.A. © 1995 by The American Society for Biochemistry and Molecular Biology, Inc. Involvement of SH2-containing Phosphotyrosine Phosphatase Syp in Erythropoietin Receptor Signal Transduction Pathways* (Received for publication, October 25, 1994, and in revised form, January 5, 1995) Tetsuzo Tauchi:j:§~,Gen-Sheng Feng§ll, Randy Shen§ll, Maureen Hoatlin**, Grover C. Bagby, Jr.**, David Kabat:j::j:, Li Lu:j:§, and Hal E. Broxmeyer:j:§§~~ From the Departments of :j:Medicine (Hematology / Oncology), IlBiochemistry and Molecular Biology, §§Microbiology and Immunology, and the §Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202 and the **Division ofHematology and Medical Oncology and HDepartment of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, Oregon 97201-3098 Erythropoietin (Epo) regulates the proliferation and EpoR and a number of cellular substrates (6-9); induction of differentiation oferythroid precursors. The phosphoryl­ transcription of several immediate-early genes (10, 11); induc­ ation of proteins at tyrosine residues is critical in the tion of the association of phosphatidylinositol 3' -kinase with growth signaling induced by Epo. This mechanism is the EpoR 02-15); activation of components of the Ras signal­ regulated by the activities of both protein-tyrosine ki­ ing 
TI - Involvement of SH2-containing Phosphotyrosine Phosphatase Syp in Erythropoietin Receptor Signal Transduction Pathways
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.270.10.5631
DA - 1995-03-01
UR - https://www.deepdyve.com/lp/unpaywall/involvement-of-sh2-containing-phosphotyrosine-phosphatase-syp-in-Asr4WS36BO
DP - DeepDyve
ER -