TY - JOUR
AU - Hwa, T
AB - The statistical mechanics of heteropolymer structure formation is studied in the context of RNA secondary structures. A designed RNA sequence biased energetically towards a particular native structure (a hairpin) is used to study the transition between the native and molten phase of the RNA as a function of temperature. The transition is driven by a competition between the energy gained from the polymer's overlap with the native structure and the entropic gain of forming random contacts. A simplified Go¯-like model is proposed and solved exactly. The predicted critical behavior is verified via exact numerical enumeration of a large ensemble of similarly designed sequences.
TI - RNA Secondary Structure Formation: A Solvable Model of Heteropolymer Folding
JF - Physical Review Letters
DO - 10.1103/PhysRevLett.83.1479
DA - 1999-08-16
UR - https://www.deepdyve.com/lp/american-physical-society-aps/rna-secondary-structure-formation-a-solvable-model-of-heteropolymer-B86GuhQAwV
SP - 1479
EP - 1482
VL - 83
IS - 7
DP - DeepDyve
ER -