TY - JOUR
AU - Fujita, Takashi
AB - Interferon (IFN) regulatory factor-3 (IRF-3) is a unique member of the IRF family. Its transcriptional activity is regulated solely by posttranslational modifications. We review current knowledge of the mechanism of IRF-3 activation: signalling triggered by infections including viruses and bacteria, phosphorylation of IRF-3 on certain serine residues, homodimer formation, and active holocomplex formation with coactivator CBP/p300.
TI - Control of IRF-3 activation by phosphorylation.
JF - Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
DO - 10.1089/107999002753452674
DA - 2002-06-17
UR - https://www.deepdyve.com/lp/pubmed/control-of-irf-3-activation-by-phosphorylation-BC5P20sfQ2
SP - 73
EP - 76
VL - 22
IS - 1
DP - DeepDyve
ER -