TY - JOUR
AU1 - Jackson, Matthew, P.
AU2 - Neill, Roger, J.
AU3 - O&apos
AU4 - Brien, Alison, D.
AU5 - Holmes, Randall, K.
AU6 - Newland, John, W.
AB - Summary The nucleotide sequence of the Shiga-like toxin type II (SLT-II) structural genes cloned from bacteriophage 933W of the enterohemorrhagic Escherichia coli O157:H7 strain 933 was determined. This sequence was compared with the published sequence for the structural genes of the antigenically distinct Shiga-like toxin type I (SLT-I) encoded by bacteriophage 933J. The SLT-I and SLT-II structural genes shared 58% overall nucleotide and 56% amino acid sequence homologies. The A and B subunits of SLT-I and SLT-II were nearly identical in size and had similar secondary structures and hydropathy plots. The regulation proposed for the SLT-II operon is similar to that previously proposed for SLT-I. Shiga-like toxin, Verotoxin, Nucleotide sequence comparison References [1] O'Brien A.D. LaVeck G.D. Thompson M.R. Formal S.B. ( 1982 ) J. Infect. Dis. , 146 , 763 – 769 . Crossref Search ADS PubMed [2] O'Brien A.D. LaVeck G.D. ( 1983 ) Infect. Immun. , 40 , 675 – 683 . PubMed [3] O'Brien A.D. Lively T.A. Chang T.W. Gorbach S.L. ( 1983 ) Lancet , II , 573 . Crossref Search ADS [4] O'Brien A.D. Lively T.A. Chen M.E. Rothman S.W. Formal S.B. ( 1983 ) Lancet , I , 702 . Crossref Search ADS [5] Marques L.R.M. Moore M.A. Wells J.G. Wachsmuth I.K. O'Brien A.D. ( 1986 ) J. Infect. Dis. , 154 , 338 – 341 . Crossref Search ADS PubMed [6] O'Brien A.D. Holmes R.K. ( 1987 ) Microbiol. Rev. , (in press). [7] Strockbine N.A. Marques L.R.M. Newland J.W. Smith H.W. Holmes R.K. O'Brien A.D. ( 1986 ) Infect. Immun. , 53 , 135 – 140 . PubMed [8] Scotland S.M. Smith H.R. Rowe B. ( 1985 ) Lancet , II , 885 – 886 . Crossref Search ADS [9] Scotland S.M. Smith H.W. Willshaw G.A. Rowe B. ( 1983 ) Lancet , II , 216 . Crossref Search ADS [10] Smith H.W. Green P. Parsell Z. ( 1983 ) J. Gen. Microbiol. , 129 , 3121 – 3137 . PubMed [11] O'Brien A.D. Newland J.W. Miller S.F. Holmes R.K. Smith H.W. Formal S.B. ( 1984 ) Science , 226 , 694 – 696 . Crossref Search ADS PubMed [12] Newland J.W. Strockbine N.A. Miller S.F. O'Brien A.D. Holmes R.K. ( 1985 ) Science , 230 , 179 – 181 . Crossref Search ADS PubMed [13] Jackson M.P. Newland J.W. Holmes R.K. O'Brien A.D. ( 1987 ) Microb. Path. , 2 , 147 – 153 . Crossref Search ADS [14] Willshaw G.A. Smith H.R. Scotland S.M. Rowe B. ( 1985 ) J. Gen. Microbiol. , 131 , 3047 – 3053 . PubMed [15] Huang A. de Grandis S. Friesen J. Karmali M. Petric M. Congi R. Brunton J.L. ( 1986 ) J. Bacteriol. , 166 , 375 – 379 . Crossref Search ADS PubMed [16] de Grandis S. Guisberg J. Climie S. Toone M. Friesen J. Brunton J. ( 1987 ), B-70 , In Abstr. Annu. Meeting Amer. Soc. Microbiol. , pp 36 . Google Scholar Google Preview OpenURL Placeholder Text WorldCat COPAC [17] Sanger F. Coulson A.R. Barvell B.G. Smith A.J.H. Roe B.A. ( 1980 ) J. Mol. Biol. , 143 , 161 – 178 . Crossref Search ADS PubMed [18] Sanger F.S. Nicklen S. Coulson A.R. ( 1977 ), 74 , In Proc. Natl. Acad. Sci. U.S.A. , pp 5463 – 5467 . Google Scholar Google Preview OpenURL Placeholder Text WorldCat COPAC [19] Biggin M.D. Gibson T.J. Hong G.F. ( 1983 ), 80 , In Proc. Natl. Acad. Sci. U.S.A. , pp 3963 – 3965 . Google Scholar Google Preview OpenURL Placeholder Text WorldCat COPAC [20] Kyte J. Doolittle R.F. ( 1982 ) J. Mol. Biol. , 157 , 105 – 132 . Crossref Search ADS PubMed [21] Oliver D. ( 1985 ) Ann. Rev. Microbiol. , 39 , 615 – 648 . Crossref Search ADS [22] Seidah N.G. Donohue-Rolfe A. Lazure C. Auclair F. Keusch G.T. Chretien M. ( 1986 ) J. Biol. Chem. , 261 , 13928 – 13931 . PubMed [23] Yutsudo T. Nakabayashi N. Hirayama T. Takeda Y. ( 1987 ) Microb. Path. , (in press). [24] Donohue-Rolfe A. Keusch G.T. Edson C. Thorley-Lawson D. Jacewicz M. ( 1984 ) J. Exp. Med. , 160 , 1767 – 1781 . Crossref Search ADS PubMed [25] Rosenberg M. Court D. ( 1979 ) Ann. Rev. Genet. , 13 , 319 – 353 . Crossref Search ADS [26] Shine J. Dalgarno L. ( 1974 ), 71 , In Proc. Natl. Acad. Sci. U.S.A. , pp 1342 – 1346 . Google Scholar Google Preview OpenURL Placeholder Text WorldCat COPAC [27] Mekalanos J.J. Swartz D.J. Pearson G.D.N. Harford N. Groyne F. DeWilde M. ( 1983 ) Nature , 306 , 551 – 557 . Crossref Search ADS PubMed [28] Oppenheim D.S. Yanofsky C. ( 1980 ) Genetics , 95 , 785 – 795 . PubMed [29] Yamamoto T. Gojobori T. Yokota T. ( 1987 ) J. Bacteriol. , 169 , 1352 – 1357 . Crossref Search ADS PubMed [30] Hori H. Osawa S. ( 1978 ) J. Bacteriol. , 133 , 1089 – 1095 . PubMed [31] Grosjean H. Friers W. ( 1982 ) Gene , 18 , 199 – 209 . Crossref Search ADS PubMed This content is only available as a PDF. © 1987 Federation of European Microbiological Societies
TI - Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages from Escherichia coli 933
JF - FEMS Microbiology Letters
DO - 10.1111/j.1574-6968.1987.tb02252.x
DA - 1987-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/nucleotide-sequence-analysis-and-comparison-of-the-structural-genes-BOYdquIQv6
SP - 109
EP - 114
VL - 44
IS - 1
DP - DeepDyve
ER -