TY - JOUR AU1 - Prathapan, Smriti AU2 - Samala, Ravi K. AU3 - Hadjiyski, Nathan AU4 - D’Haese, Pierre-François AU5 - Maldonado, Fabien AU6 - Nguyen, Phuong AU7 - Yesha, Yelena AU8 - Sahiner, Berkman AB - Devices enabled by artificial intelligence (AI) and machine learning (ML) are being introduced for clinical use at an accelerating pace. In a dynamic clinical environment, these devices may encounter conditions different from those they were developed for. The statistical data mismatch between training/initial testing and production is often referred to as data drift. Detecting and quantifying data drift is significant for ensuring that AI model performs as expected in clinical environments. A drift detector signals when a corrective action is needed if the performance changes. In this study, we investigate how a change in the performance of an AI model due to data drift can be detected and quantified using a cumulative sum (CUSUM) control chart. To study the properties of CUSUM, we first simulate different scenarios that change the performance of an AI model. We simulate a sudden change in the mean of the performance metric at a change-point (change day) in time. The task is to quickly detect the change while providing few false-alarms before the change-point, which may be caused by the statistical variation of the performance metric over time. Subsequently, we simulate data drift by denoising the Emory Breast Imaging Dataset (EMBED) after a pre-defined change-point. We detect the change-point by studying the pre- and post-change specificity of a mammographic CAD algorithm. Our results indicate that with the appropriate choice of parameters, CUSUM is able to quickly detect relatively small drifts with a small number of false-positive alarms. TI - Quantifying input data drift in medical machine learning models by detecting change-points in time-series data JF - Progress in Biomedical Optics and Imaging - Proceedings of SPIE DO - 10.1117/12.3008771 DA - 2024-04-03 UR - https://www.deepdyve.com/lp/spie/quantifying-input-data-drift-in-medical-machine-learning-models-by-BpLyRVRt6U SP - 129270E EP - 129270E-10 VL - 12927 IS - DP - DeepDyve ER -