TY - JOUR
AU - Thornton, Janet M.
AB - EC-BLAST is an algorithm for quantitative similarity searches between enzyme reactions at three levels a) bond change, b) reaction centre and c) reaction structure similarity. It exploits the knowledge of bond changes and reaction patterns for all known biochemical reactions derived from atom-atom mapping (AAM) across each reaction. This has the potential to improve the established enzyme classification system, to find novel biochemical transformations, to improve the assignment of enzyme function to sequences, as well as for the re-engineering of enzymes.EC-BLAST URL: http://www.ebi.ac.uk/thornton-srv/software/rbl/
TI - EC-BLAST: A Tool to Automatically Search and Compare Enzyme Reactions
JF - Nature Methods
DO - 10.1038/nmeth.2803
DA - 2014-01-12
UR - https://www.deepdyve.com/lp/pubmed-central/ec-blast-a-tool-to-automatically-search-and-compare-enzyme-reactions-Bz44CvPjpU
SP - 171
EP - 174
VL - 11
IS - 2
DP - DeepDyve
ER -