TY - JOUR AU - AB - University of Dundee Discovery of XL01126 Liu, Xingui; Kalogeropulou, Alexia F.; Domingos, Sofia; Makukhin, Nikolai; Nirujogi, Raja; Singh, Francois Published in: Journal of the American Chemical Society DOI: 10.1021/jacs.2c05499 Publication date: Licence: CC BY Document Version Publisher's PDF, also known as Version of record Link to publication in Discovery Research Portal Citation for published version (APA): Liu, X., Kalogeropulou, A. F., Domingos, S., Makukhin, N., Nirujogi, R., Singh, F., Shpiro, N., Saalfrank, A., Sammler, E., Ganley, I. G., Moreira, R., Alessi, D. R., & Ciulli, A. (2022). Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine- Rich Repeat Kinase 2. Journal of the American Chemical Society, 144(37), 16930-16952. https://doi.org/10.1021/jacs.2c05499 General rights Copyright and moral rights for the publications made accessible in Discovery Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. Take down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Download date: 16. Jun. 2024 pubs.acs.org/JACS Article TI - Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2 JF - Journal of the American Chemical Society DO - 10.1021/jacs.2c05499 DA - 2022-08-25 UR - https://www.deepdyve.com/lp/unpaywall/discovery-of-xl01126-a-potent-fast-cooperative-selective-orally-CACHLtzAdN DP - DeepDyve ER -