TY - JOUR
AU1 - Toda, Yoshimi
AU2 - Saito, Rintaro
AU3 - Tomita, Masaru
AB -  We conducted comprehensive sequence analysis of 5′ flanking regions of primate Alu elements. Information contents were computed and frequencies of 1024 pentanucleotides were measured to approximate the location of a characteristic sequence and to specify its pattern(s), which may be involved in the integration of Alu elements into their host genomes. A large number of samples was used, the wide region of the 5′ end of Alu elements was analyzed, and comparisons were made among different subfamilies. Through our analyses, ``TTTTAAAAA'' or ``(T)
m
(A)
n
'' can be stated as a candidate for the characteristic sequence pattern, which resides around the region 5 to 20 base pairs upstream of the 5′ end of Alu elements. This characteristic sequence pattern was more prominent in the sequences of younger Alus, which is a strong indication that the sequence pattern has a role at the time of Alu integration.
TI - Characteristic Sequence Pattern in the 5- to 20-bp Upstream Region of Primate Alu Elements
JF - Journal of Molecular Evolution
DO - 10.1007/s002399910026
DA - 2000-03-01
UR - https://www.deepdyve.com/lp/springer-journals/characteristic-sequence-pattern-in-the-5-to-20-bp-upstream-region-of-CBfM97kZM5
SP - 232
EP - 237
VL - 50
IS - 3
DP - DeepDyve
ER -