TY - JOUR AU - Miranda, Miguel A AB - Norfloxacin (NFX) photosensitizes formation of thymine dimers (T<>T) in DNA, while its N(4') acetyl derivative (ANFX) does not. This is evident from the observation of single-strand breaks after enzymatic treatment with T4 endonuclease V and subsequent gel electrophoresis. The triplet energies of NFX and ANFX are estimated at 273 and 268 kJ/mol, respectively, on the basis of triplet-triplet energy transfer quenching by a set of biphenyl and naphthalene derivatives. Hence, the triplet energy of thymine in DNA (i.e., the value for a photosensitizer to produce T<>T) can be estimated at 270 kJ/mol. TI - The triplet energy of thymine in DNA. JF - Journal of the American Chemical Society DO - 10.1021/ja060651g DA - 2007-06-27 UR - https://www.deepdyve.com/lp/pubmed/the-triplet-energy-of-thymine-in-dna-Cwr2yHCCza SP - 6318 EP - 9 VL - 128 IS - 19 DP - DeepDyve ER -