TY - JOUR
AU - Levine, V.J.
AB - 670 Correspondence 10 Yamauchi T, Kamon J, Waki H et al. The fat-derived hormone which secrete a number of cytokines, including interferon adiponectin reverses insulin resistance associated with both lipo- (IFN)-a, that lead to activation, bridging and induction of atrophy and obesity. Nat Med 2001; 7:941–6. innate and adaptive immunity, leading to psoriasis. The role of IFN-a in psoriasis is based on several observations. Firstly, Funding sources: this work was supported by grants from the Ministry treatment with type I IFN (interferon alfa and interferon beta) of Education, Culture, Sports, Science, and Technology of Japan. for a number of unrelated conditions (hepatitis C, chronic 6 7 Conflicts of interest: none declared. myeloid leukaemia, multiple myeloma ) can induce or exac- erbate psoriasis. Secondly, the type I IFN signalling pathway is upregulated in psoriatic lesions compared with nonlesional skin and T cells within psoriatic plaques have an increased Imiquimod 5% cream induced psoriasis: a response to IFN-a. Thirdly, constitutive activation of type I case report, summary of the literature and IFN signalling in mice lacking IFN regulatory factor 2, a tran- mechanism scriptional attenuator of IFN-a ⁄b, leads to psoriasis-like inflammatory skin disease. In a xenograft murine model of DOI: 
TI - Imiquimod 5% cream induced psoriasis: a case report, summary of the literature and mechanism
JF - British Journal of Dermatology
DO - 10.1111/j.1365-2133.2010.10124.x
DA - 2011-03-01
UR - https://www.deepdyve.com/lp/oxford-university-press/imiquimod-5-cream-induced-psoriasis-a-case-report-summary-of-the-DBACgNA9t2
SP - 670
EP - 672
VL - 164
IS - 3
DP - DeepDyve
ER -