TY - JOUR AU - AB - Citation: Rahman A, Sahrin M, Afrin S, Earley K, Ahmed S, Rahman SMM, et al. (2016) Comparison of Xpert MTB/RIF Assay and GenoType MTBDRplus Background DNA Probes for Detection of Mutations Associated with Rifampicin Resistance in Mycobacterium GeneXpert MTB/RIF (Xpert) and Genotype MTBDRplus (DRplus) are two World Health tuberculosis. PLoS ONE 11(4): e0152694. Organization (WHO) endorsed probe based molecular drug susceptibility testing (DST) doi:10.1371/journal.pone.0152694 methods for rapid diagnosis of drug resistant tuberculosis. Both methods target the same Editor: Riccardo Manganelli, University of Padova, 81 bp Rifampicin Resistance Determining Region (RRDR) of bacterial RNA polymerase β Medical School, ITALY subunit (rpoB) for detection of Rifampicin (RIF) resistance associated mutations using DNA Received: December 22, 2015 probes. So there is a correspondence of the probes of each other and expected similarity of Accepted: March 17, 2016 probe binding. Published: April 7, 2016 Methods Copyright: © 2016 Rahman et al. This is an open access article distributed under the terms of the We analyzed 92 sputum specimens by Xpert, DRplus and LJ proportion method (LJ-DST). Creative Commons Attribution License, which permits We compared molecular DSTs with gold standard LJ-DST. We wanted to see the agree- unrestricted use, distribution, and reproduction in any TI - Comparison of Xpert MTB/RIF Assay and GenoType MTBDRplus DNA Probes for Detection of Mutations Associated with Rifampicin Resistance in Mycobacterium tuberculosis JF - PLoS ONE DO - 10.1371/journal.pone.0152694 DA - 2016-04-07 UR - https://www.deepdyve.com/lp/unpaywall/comparison-of-xpert-mtb-rif-assay-and-genotype-mtbdrplus-dna-probes-DovOAdYg9J DP - DeepDyve ER -