TY - JOUR
AU1 - MacIntyre, R J
AB -  The existence of duplications of parts of chromosomes and of specific genetic loci was inferred in Drosophila by Bridges (39) and Sturtevant (280) early in this cen­ tury. In his address as the retiring president of the American Society of Naturalists in 1947, Metz (201 ), however, could point to only a few specific instances of duplicate bands after cytological studies on the polytene chromosomes from Dipt­ eran insects. Stephens, in a 195 1 review of the significance of duplications in evolu­ tion, concluded that there was not a single proven case in which two gene products could be homologously related (273). These and other students of evolution [see (273) for references] were certainly aware that new genetic material must come from duplications of previously existing genes or chromosomes. Metz even surmised correctly that some duplicate genes might be unstable and that heterochromatin may contain "repeated chromosomal parts." Nevertheless, before the advent of molecular biology, essentially only speculation about the extent and the �elective importance of duplicate genes was available. Now, however, while there is still no shortage of speculation about this phenomenon and its evolutionary meaning, there are many firmly documented cases of duplicate genes, including those 
TI - Evolution and Ecological Value of Duplicate Genes
JF - Annual Review of Ecology, Evolution, and Systematics
DO - 10.1146/annurev.es.07.110176.002225
DA - 1976-11-01
UR - https://www.deepdyve.com/lp/annual-reviews/evolution-and-ecological-value-of-duplicate-genes-E40nxMJa0G
SP - 421
EP - 468
VL - 7
IS - 1
DP - DeepDyve
ER -