TY - JOUR AU - Wang, Ting AB - correspond ence 3–5 exhibit coherent but distinct global patterns of CNA (Fig. 1b–e and Supplementary Fig. 1). Breast cancer tumors had characteristic ampli- fications on chromosomes 1q and 8; glioblastomas had amplifications To the Editor: Advances in high-throughput genomics have reshaped on 7 and deletions on chromosomes 9p, 10, 13 and 14. To explore the cancer research landscape. Complete characterization of genomic, detailed patterns in a particular genomic region, the genome heatmap epigenomic and transcriptomic changes of tumors, combined with allows users to zoom and pan (Fig. 1f), and ultimately enter the UCSC 1,2 clinical characterization, will help predict pathological behavior and Genome Browser to examine data from individual samples in small effective treatments. However, comprehensive analysis of the cancer regions (Supplementary Fig. 1f). Use of browser utilities (including genome remains a daunting challenge. We must visualize, integrate, the pathway sorter and feature sorter) highlights biological insights, compare and analyze large cancer genomics datasets. Ultimately, these as illustrated in a comparison of gene expression classifiers for out- data and the resulting conclusions must be presented to the scientific come prediction for individuals with breast cancer (Supplementary and medical communities in a coherent, integrated system for display Notes and Supplementary TI - The UCSC Cancer Genomics Browser JF - Nature Methods DO - 10.1038/nmeth0409-239 DA - 2009-04-01 UR - https://www.deepdyve.com/lp/springer-journals/the-ucsc-cancer-genomics-browser-E5mI407h8y SP - 239 EP - 240 VL - 6 IS - 4 DP - DeepDyve ER -