TY - JOUR AU - Fujimoto, Wilfred Y. AB - Visceral Adiposity and the Prevalence of Hypertension in Japanese Americans Tomoshige Hayashi, MD, PhD; Edward J. Boyko, MD, MPH; Donna L. Leonetti, PhD; Marguerite J. McNeely, MD, MPH; Laura Newell-Morris, PhD; Steven E. Kahn, MB, ChB; Wilfred Y. Fujimoto, MD Background—Visceral adiposity is generally considered to play a key role in the metabolic syndrome, including hypertension. The purpose of this study was to evaluate cross-sectionally whether visceral adiposity is associated with prevalence of hypertension independent of other adipose depots and fasting plasma insulin. Methods and Results—Study subjects included 563 Japanese Americans with normal or impaired glucose tolerance or diabetes but not taking oral hypoglycemic medication or insulin at entry. Variables included plasma glucose and insulin measured after an overnight fast and during an oral glucose tolerance test, and abdominal, thoracic, and thigh fat areas by CT. Total fat area (TFA) was calculated as the sum of these fat areas. Hypertension was defined as having a systolic blood pressure 140 mm Hg, having a diastolic blood pressure 90 mm Hg, or taking antihypertensive medications. Intra-abdominal fat area (IAFA) was associated with a higher prevalence of hypertension. Adjusted odds ratio of hypertension by IAFA was 1.68 for a 1-SD increase (95% TI - Visceral Adiposity and the Prevalence of Hypertension in Japanese Americans JF - Circulation DO - 10.1161/01.CIR.0000087597.59169.8D DA - 2003-10-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/visceral-adiposity-and-the-prevalence-of-hypertension-in-japanese-FZrKFj0env SP - 1718 EP - 1723 VL - 108 IS - 14 DP - DeepDyve ER -