TY - JOUR
AU - 
AB - SAGE-Hindawi Access to Research International Journal of Alzheimer’s Disease Volume 2011, Article ID 505607, 23 pages doi:10.4061/2011/505607 Review Article What Are the bona fide GSK3 Substrates? Calum Sutherland Biomedical Research Institute, University of Dundee, Dundee DD1 9SY, UK Correspondence should be addressed to Calum Sutherland, c.d.sutherland@dundee.ac.uk Received 9 February 2011; Accepted 9 March 2011 Academic Editor: Adam Cole Copyright © 2011 Calum Sutherland. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Nearly 100 proteins are proposed to be substrates for GSK3, suggesting that this enzyme is a fundamental regulator of almost every process in the cell, in every tissue in the body. However, it is not certain how many of these proposed substrates are regulated by GSK3 in vivo. Clearly, the identification of the physiological functions of GSK3 will be greatly aided by the identification of its bona fide substrates, and the development of GSK3 as a therapeutic target will be highly influenced by this range of actions, hence the need to accurately establish true GSK3 substrates in cells. In this paper the evidence that proposed GSK3 
TI - What Are the <i>bona fide</i> GSK3 Substrates?
JF - International Journal of Alzheimer s Disease
DO - 10.4061/2011/505607
DA - 2011-01-01
UR - https://www.deepdyve.com/lp/unpaywall/what-are-the-i-bona-fide-i-gsk3-substrates-G23zFL57UR
DP - DeepDyve
ER -