TY - JOUR
AU - 
AB - fnmol-15-844193 March 8, 2022 Time: 14:33 # 1 REVIEW published: 14 March 2022 doi: 10.3389/fnmol.2022.844193 Roles of Long Non-coding RNAs in the Development of Aging-Related Neurodegenerative Diseases 1,2 1,2 1,2 Yu-Qing Ni , Hui Xu and You-Shuo Liu * 1 2 Department of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha, China, Institute of Aging and Age-Related Disease Research, Central South University, Changsha, China Aging-related neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are gradually becoming the primary burden of society and cause significant health-care concerns. Aging is a critical independent risk factor for neurodegenerative diseases. The pathological alterations of neurodegenerative diseases are tightly associated with mitochondrial dysfunction, inflammation, and oxidative stress, which in turn stimulates the further progression of neurodegenerative diseases. Given the potential research value, lncRNAs have attracted considerable attention. LncRNAs play complex and dynamic roles in multiple signal transduction axis of neurodegeneration. Emerging evidence indicates that lncRNAs exert crucial regulatory effects in the initiation Edited by: Erquan Zhang, and development of aging-related neurodegenerative diseases. This review compiles the National Institute of Biological underlying pathological mechanisms of aging and related neurodegenerative diseases. Sciences (NIBS), China Besides, 
TI - Roles of Long Non-coding RNAs in the Development of Aging-Related Neurodegenerative Diseases
JF - Frontiers in Molecular Neuroscience
DO - 10.3389/fnmol.2022.844193
DA - 2022-03-14
UR - https://www.deepdyve.com/lp/unpaywall/roles-of-long-non-coding-rnas-in-the-development-of-aging-related-G2SQBo5LLN
DP - DeepDyve
ER -