TY - JOUR AU - Spencer, Robin W. AB - At Pfizer Central Research, high‐throughput screening has been an important source of new leads for drug discovery for a decade. Our experience with over 150 high‐throughput screens can address questions about necessary file size, how well particular biological targets fare (with particular reference to protein‐protein interactions), and what file diversity means in practice. © 1998 John Wiley & Sons, Inc. Biotechnol Bioeng (Comb Chem) 61:61–67, 1998. TI - High‐throughput screening of historic collections: Observations on file size, biological targets, and file diversity JF - Biotechnology and Bioengineering DO - 10.1002/(SICI)1097-0290(199824)61:1<61::AID-BIT11>3.0.CO;2-C DA - 1998-01-01 UR - https://www.deepdyve.com/lp/wiley/high-throughput-screening-of-historic-collections-observations-on-file-H03PERy0Yu SP - 61 EP - 67 VL - 61 IS - 1 DP - DeepDyve ER -