TY - JOUR AU - Schnitzer, Thomas J. AB - GUIDELINES FOR THE MEDICAL MANAGEMENT OF OSTEOARTHRITIS Part 11. Osteoarthritis of the Knee MARC C. HOCHBERG, ROY D. ALTMAN, KENNETH D. BRANDT, BRUCE M. CLARK, PAUL A. DIEPPE, MARIE R. GRIFFIN, ROLAND W. MOSKOWITZ, and THOMAS J. SCHNITZER Osteoarthritis (OA), previously called degenerative joint disease, is the most prevalent form of arthritis in the United States (1). Clinically, patients with OA of the knee have pain in and around the knee that is typically worse with weight-bearing and improved with rest, morning stiffness, and gel phenomenon, and, on physical examination, often have tenderness to palpation, bony enlargement, crepitus on motion, and/or limitation of joint motion. Unlike rheumatoid arthritis and other inflammatory arthritides, inflammation, if present, is usually mild. Although the causes of OA of the knee are not always known, biomechanical stresses affecting the articular cartilage and subchondral bone and biochemical changes in the articular cartilage and synovial membrane are important in its pathogenesis (2-4). Guidelines for the medical management of patients with OA of the hip are reported in an accompaSupported by a grant from the Arthritis Foundation. The Arthritis Foundation received an unrestricted grant from McNeil Consumer Products Company. Approved by the Board of Directors, American TI - Guidelines for the medical management of osteoarthritis JF - Arthritis & Rheumatism DO - 10.1002/art.1780381104 DA - 1995-11-01 UR - https://www.deepdyve.com/lp/wiley/guidelines-for-the-medical-management-of-osteoarthritis-H0EEMqwNWd SP - 1541 EP - 1546 VL - 38 IS - 11 DP - DeepDyve ER -