TY - JOUR
AU - O’Shea, John
AB - Janus kinases (Jaks) are critical signaling elements for a large subset of cytokines. As a consequence they play
pivotal roles in the patho-physiology of many diseases including neoplastic and autoimmune diseases. Small molecule Jak
inhibitors as therapeutic agents have become a reality and the palette of such inhibitors will likely expand. This review
will summarize our current knowledge on these key enzymes and their associated pharmaceutical inhibitors.
TI - JAK Kinases in Health and Disease: An Update
JF - The Open Rheumatology Journal
DO - 10.2174/1874312901206010232
DA - 2012-09-07
UR - https://www.deepdyve.com/lp/pubmed-central/jak-kinases-in-health-and-disease-an-update-H9v3uoDlSb
SP - 232
EP - 244
VL - 6
IS - 
DP - DeepDyve
ER -