TY - JOUR
AU - Hu, Dongsheng
AB - Suggested citation for this article: Qie R, Liu L, Zhang D, Han M, Wang B, Zhao Y, et al. Dose–Response Association Between Introduction High-Density Lipoprotein Cholesterol and Stroke: A Systematic Studies investigating the effect of high-density lipoprotein choles- Review and Meta-Analysis of Prospective Cohort Studies. Prev terol (HDL-C) on stroke and stroke subtypes have reached incon- Chronic Dis 2021;18:200278. DOI: https://doi.org/10.5888/ sistent conclusions. The purpose of our study was to clarify the pcd18.200278. dose–response association between HDL-C level and risk of total stroke and stroke subtypes by a systematic review and meta- analysis. PEER REVIEWED Methods Summary We performed a systematic search of PubMed, Embase, and Web What is already known on this subject? of Science databases through July 30, 2020, for prospective co- hort studies that reported the HDL-C–stroke association and ex- Previous epidemiologic studies reported that HDL-C protected against the development of stroke. However, several recent cohort studies found a tracted the estimate that was adjusted for the greatest number of positive association between HDL-C level and intracerebral hemorrhage. confounding factors. Restricted cubic splines were used to evalu- Also, whether a dose–response association between HDL-C level and ate the linear and nonlinear dose–response associations. stroke subtypes exists 
TI - Dose–Response Association Between High-Density Lipoprotein Cholesterol and Stroke: A Systematic Review and Meta-Analysis of Prospective Cohort Studies
JF - Preventing Chronic Disease
DO - 10.5888/pcd18.200278
DA - 2021-05-11
UR - https://www.deepdyve.com/lp/unpaywall/dose-response-association-between-high-density-lipoprotein-cholesterol-Iihe0d1vAh
DP - DeepDyve
ER -