TY - JOUR
AU - Andrew Rambaut, Nicholas C. Grass
AB - Motivation: Seq-Gen is a program that will simulate the evolution of nucleotide sequences along a phylogeny, using common models of the substitution process. A range of models of molecular evolution are implemented, including the general reversible model. Nucleotide frequencies and other parameters of the model may be given and site-specific rate heterogeneity can also be incorporated in a number of ways. Any number of trees may be read in and the program will produce any number of data sets for each tree. Thus, large sets of replicate simulations can be easily created. This can be used to test phylogenetic hypotheses using the parametric bootstrap. Availability: Seq-Gen can be obtained by WWW from http://evolve.zoo.ox.ac.uk/Seq-Gen/seq-gen.html or by FTP from ftp://evolve.zoo.ox.ac.uk/packages/Seq-Gen/ . The package includes the source code, manual and example files. An Apple Macintosh version is available from the same sites. © Oxford University Press « Previous | Next Article » Table of Contents This Article Comput Appl Biosci (1997) 13 (3): 235-238. doi: 10.1093/bioinformatics/13.3.235 » Abstract Free Full Text (PDF) Free Classifications Original Paper Services Article metrics Alert me when cited Alert me if corrected Alert me if commented Find similar articles Similar articles in Web of Science Similar articles in PubMed Add to my archive Download citation Request Permissions Responses Submit a response No responses published Citing Articles Load citing article information Citing articles via CrossRef Citing articles via Scopus Citing articles via Web of Science Citing articles via Google Scholar Google Scholar Articles by Rambaut, A. Articles by Grass, N. C. Search for related content PubMed PubMed citation Articles by Rambaut, A. Articles by Grass, N. C. 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TI - Seq-Gen: an application for the Monte Carlo simulation of DNA sequence evolution along phylogenetic trees
JF - Bioinformatics
DO - 10.1093/bioinformatics/13.3.235
DA - 1997-06-01
UR - https://www.deepdyve.com/lp/oxford-university-press/seq-gen-an-application-for-the-monte-carlo-simulation-of-dna-sequence-KUVj4pJwSi
SP - 235
VL - 13
IS - 3
DP - DeepDyve
ER -