TY - JOUR AU1 - Gratz, Scott J. AU2 - Cummings, Alexander M. AU3 - Nguyen, Jennifer N. AU4 - Hamm, Danielle C. AU5 - Donohue, Laura K. AU6 - Harrison, Melissa M. AU7 - Wildonger, Jill AU8 - O’Connor-Giles, Kate M. AB - We have adapted a bacterial CRISPR RNA/Cas9 system to precisely engineer the Drosophila genome and report that Cas9-mediated genomic modifications are efficiently transmitted through the germline. This RNA-guided Cas9 system can be rapidly programmed to generate targeted alleles for probing gene function in Drosophila. TI - Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease JF - Genetics DO - 10.1534/genetics.113.152710 DA - 2013-08-01 UR - https://www.deepdyve.com/lp/pubmed-central/genome-engineering-of-drosophila-with-the-crispr-rna-guided-cas9-Lhctn0vjFS SP - 1029 EP - 1035 VL - 194 IS - 4 DP - DeepDyve ER -