TY - JOUR AU - De Robertis, E. M. AB - Evolutionary biology logues were not implicated in the formation of vertebrate somites. In fact, many homo­ logues of Drosophila segment-polarity genes (such as engrailed, wingless, armadillo, hedge­ E. M. De Robertis hog and patched) have been found to have other functions in vertebrates, such as the ntil recently, most evolutionary biol­ formation of the midbrain-hindbrain border and dorsoventral patterning of the neural U ogists would have agreed that the segments of an arthropod, such as an tube. The newwork will undoubtedly stimu­ late a second, hard look for expression of these insect, and of the backbone of a vertebrate were independent ('convergent') solutions homologues in forming somites in regions such as the tailbud of the vertebrate embryo. to a functional need for building bilaterally symmetrical body plans using modular Figure 1 Expression of engrailed mRNA in the In zebrafish, chick and mouse, engrailed units. The work reported by Linda Holland posterior portion of each of the five somites that homologues are expressed in subsets of cells in 7 8 and colleagues in the May issue of Develop­ have been formed in a 12-hour amphioxus the somites ' , but only after somites have been embryo. The sixth stripe is TI - The ancestry of segmentation JF - Nature DO - 10.1038/387025a0 DA - 1997-05-01 UR - https://www.deepdyve.com/lp/springer-journals/the-ancestry-of-segmentation-M2MYtmAwmT SP - 25 EP - 26 VL - 387 IS - 6628 DP - DeepDyve ER -