TY - JOUR
AU - Holbrook, Nikki, J.
AB - Introduction and Background Modern glucocorticoid endocrinology is a colorful, richly varied, but formless discipline—a profusion of cellular, physiological and pharmacological effects, seemingly unrelated through any central hormonal function. A current list of glucocorticoid effects might include such disparate items as stimulation of hepatic gluconeogenesis, inhibition of glucose uptake by peripheral tissues, suppression of inflammation, enhanced excretion of a water load, induction in various cells of tryptophan oxygenase and glutamine synthetase, suppression of numerous immune reactions, inhibition of secretion of several hormones and neuropeptides, and inhibition of activity of plasminogen activator and other neutral proteinases. Judging from recent writings on glucocorticoid physiology, an item that might be low on the list or missing altogether is “increased resistance to stress”. This content is only available as a PDF. Author notes * The work of the authors described in this review was supported by USPHS Research Grants AM-03535 and CA-17323, by the Core Grant(CA-23108) of the Norris Cotton Cancer Center, and by a grant from the Kroc Foundation. † To whom correspondence should be addressed. ‡ Nikki Holbrook was supported during part of this time by National Service Award CA-09367, and is currently a Fellow of the Leukemia Society of America. Present address: Laboratory of Pathology, National Cancer Institute, Building 10, Room 2N-113, Bethesda, Maryland 20205 Copyright © 1984 by The Endocrine Society
TI - Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions
JF - Endocrine Reviews
DO - 10.1210/edrv-5-1-25
DA - 1984-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/physiological-functions-of-glucocorticoids-in-stress-and-their-M3pQXMADgQ
SP - 25
VL - 5
IS - 1
DP - DeepDyve
ER -