TY - JOUR
AU - 
AB - REVIEW ARTICLE published: 06 August 2014 BIOENGINEERING AND BIOTECHNOLOGY doi: 10.3389/fbioe.2014.00026 Immunological and technical considerations in application of alginate-based microencapsulation systems 1 1,2 1 1 Genaro Alberto Paredes Juárez *, Milica Spasojevic , Marijke M. Faas and Paul de Vos Section of Immunoendocrinology, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Groningen, Netherlands Edited by: Islets encapsulated in immunoprotective microcapsules are being proposed as an alter- Jian Yang, The Pennsylvania State native for insulin therapy for treatment of type 1 diabetes. Many materials for producing University, USA microcapsules have been proposed but only alginate does currently qualify as ready for Reviewed by: clinical application. However, many different alginate-based capsule systems do exist. A Yi Hong, University of Texas at pitfall in the field is that these systems are applied without a targeted strategy with vary- Arlington, USA Sangamesh G. Kumbar, University of ing degrees of success as a consequence. In the current review, the different properties Connecticut, USA of alginate-based systems are reviewed in view of future application in humans. The use *Correspondence: of allogeneic and xenogeneic islet sources are 
TI - Immunological and Technical Considerations in Application of Alginate-Based Microencapsulation Systems
JF - Frontiers in Bioengineering and Biotechnology
DO - 10.3389/fbioe.2014.00026
DA - 2014-08-06
UR - https://www.deepdyve.com/lp/unpaywall/immunological-and-technical-considerations-in-application-of-alginate-M6Hm6uZzDd
DP - DeepDyve
ER -