TY - JOUR AU - AB - healthcare Review What People Want to Know About Their Genes: A Critical Review of the Literature on Large-Scale Genome Sequencing Studies 1 , 2 1 1 Courtney L. Scherr *, Sharon Aufox , Amy A. Ross , Sanjana Ramesh , 2 2 Catherine A. Wicklund and Maureen Smith Center for Communication and Health, Department of Communication Studies, Northwestern University, 710 North Lake Shore Drive, 15th Floor, Chicago, IL 60611; USA; amyross2019@u.northwestern.edu (A.A.R.); sanjanaramesh2022@u.northwestern.edu (S.R.) Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Suite 630, Chicago, IL 60611, USA; s-aufox@northwestern.edu (S.A.); c-wicklund@northwestern.edu (C.A.W.); m-smith6@northwestern.edu (M.S.) * Correspondence: courtney.scherr@northwestern.edu; Tel.: +1-312-503-7209 Received: 13 June 2018; Accepted: 30 July 2018; Published: 8 August 2018 Abstract: From a public health perspective, the “All of Us” study provides an opportunity to isolate targeted and cost-effective prevention and early-detection strategies. Identifying motivations for participation in large-scale genomic sequencing (LSGS) studies, and motivations and preferences to receive results will help determine effective strategies for “All of Us” study implementation. This paper offers a critical review of the literature regarding LSGS for adult onset hereditary conditions where results could indicate an increased risk to develop disease. The purpose of this review TI - What People Want to Know About Their Genes: A Critical Review of the Literature on Large-Scale Genome Sequencing Studies JF - Healthcare DO - 10.3390/healthcare6030096 DA - 2018-08-08 UR - https://www.deepdyve.com/lp/unpaywall/what-people-want-to-know-about-their-genes-a-critical-review-of-the-NX0FGHteEE DP - DeepDyve ER -