TY - JOUR
AU1 - Griffiths, Robert
AU2 - Bleecker, Giselle
AU3 - Jabs, Douglas
AU4 - Dieterich, Douglas
AU5 - Coleson, Laura
AU6 - Winters, Debbie
AU7 - Wolitz, Richard
AU8 - Steinberg, Earl
AB - A decision-analytical simulation model was constructed to perform a pharmacoeconomic analysis of the following 3 treatment strategies for previously untreated cytomegalovirus (CMV) retinitis in patients with AIDS: (i) intravenous foscarnet (IVF) for induction and maintenance therapy; (ii) intravenous ganciclovir (IVG) for induction and maintenance therapy; and (iii) intravenous ganciclovir for induction therapy, followed by oral ganciclovir for maintenance therapy (IVG-ORG). Patients who experienced significant adverse effects during, or who failed, initial therapy were switched once to one of the other 2 treatments. The model was used to estimate the direct medical cost (from the perspective of a public payer), survival, and survival adjusted for disutility because of lost vision, for each strategy in the first year following treatment initiation.
TI - Pharmacoeconomic Analysis of 3 Treatment Strategies for Cytomegalovirus Retinitis in Patients with AIDS
JF - PharmacoEconomics
DO - 10.2165/00019053-199813040-00008
DA - 2012-10-18
UR - https://www.deepdyve.com/lp/springer-journals/pharmacoeconomic-analysis-of-3-treatment-strategies-for-OQ4FA1Br77
SP - 461
EP - 474
VL - 13
IS - 4
DP - DeepDyve
ER -